Helmut G. Hinghofer-Szalkay: Spaceflight Research, Consultancy & Publications

Background Biography List of publications Projects front page

• ESA Publications
• Consultancy
• BBAF-Course
• NASA publications
• Other spaceflight-relevant publications
• Book on Austro-Russian spaceflight research
• Cooperation with NASA-ARC

• Hinghofer-Szalkay H. Physiology of cardiovascular, respiratory, interstitial, endocrine, immune, and muscular systems. In: D. Moore, P. Bie, H. Oser (eds): Biological and Medical Research in Space. 1996; pp. 107-53. Springer-Verlag Berlin Heidelberg New York.
• Hinghofer-Szalkay H. Achievements in medical research in space. esa sp-385, 1996;  pp. 67-73 (Space Station Utilisation Symposium, Darmstadt, Germany, 30 September-2 October 1996). ISBN 92-9092-223-0
• Hinghofer-Szalkay H, Moore D. Some comments on biological aspects of life support systems. In: D. Moore, P. Bie, H. Oser (eds): Biological and Medical Research in Space. 1996; pp. 542-61. Springer-Verlag Berlin Heidelberg New York.
• Hinghofer-Szalkay H. Physiology - Introduction to Ch. 3. , pp. 94-5; Cardiovascular system, Ch. 3.2, pp. 95-102; Respiratory system, Ch. 3.3, pp. 103-11; Interstitial space & fluid regulation, Ch. 3.4, pp. 112-6; Endocrine system, Ch. 3.5, pp. 117-21; Immune system, Ch. 3.6, pp. 122-6; Musculo-skeletal system, Ch. 3.7, pp. 127-36; Cardiovascular system, Ch. 3.1, pp. 95-102; Bioregenerative Life Support Systems, pp. 409-11; Food, nutrition, metabolism, pp. 411-20; Countermeasures, pp. 420-6. In: Focused Science in the ESA Microgravity Programme - A Review of Life Sciences Research in Space; European Space Agency, Paris 1994.
• Hinghofer-Szalkay H. Human physiology research in space. Microgravity News 1991; 4: 21-8.
• Benson A, Bonde-Petersen F, Hinghofer-Szalkay H, Kirsch K, Klein KE, Milhaud C, Stegemann J. Physiology and Medicine. 1989; pp. 5-30. In: European Space Agency SP-1105.
• Hinghofer-Szalkay H. Gravity and biological systems. Emphasis on human physiology (N. Longdon, Ed.). ESA BR-21, 1984; 26 pp.  ESTEC, Noordwijk 1984.
• Bonde-Petersen F, Hinghofer-Szalkay H, Hordinsky J. Microgravity as an additional tool for research in human physiology. 1982; 53 pp. European Space Agency BR-09.
• Hinghofer-Szalkay H. Tilt table and related studies. In: Zero-g simulation for ground-based studies in human physiology, with emphasis on the cardiovascular and body fluid systems. 1982; pp. 81-102. European Space Agency SP-180.
• Hinghofer-Szalkay H. Analysis of proposals submitted to ESA concerning space-related cardiovascular research, with emphasis on human physiology. Life 1981; (81)1. European Space Agency, Paris.

for the European Space Agency (esa)

for Aerospace Companies (Dornier, Germany; Matra, France; Carrar, France; ORS, Austria) on the following topics:

• Nutrition during long-duration spaceflight
• Biological experiments on a man-tended free flyer
• Fluid-electrolyte shifts with extended periods of weightlessness
• Freezer-cooler development for Space Station
• Neurobiology: body fluid systems
• Anthrolab

BBAF-Course

Together with W. Petek and G. Dohr, H. Hinghofer-Szalkay organized a tutorial on biology, physiology, and biochemistry for European space technicians ('BBAF-Course') in Graz, Austria (April 7-12, 1986). Contents:

• Essentials of cell biology
• Sample collection and processing
• Immunological techniques
• Biochemical and biophysical techniques
• Clinical chemistry and physiology
• Morphological techniques.

• Hinghofer-Szalkay HG. The Brittle Bones of Deconditioning, in: JE Greenleaf (ed).: Deconditioning: A Treatise for Physicisans. Taylor and Francis, London (in print)
• Greenleaf JE, H. Hinghofer-Szalkay, A Roessler, PA Farrell, JL Loomis, M Federle, J West, SE Cowell. Plasma sodium-osmotic dissociation and hormonal interaction with drinking-induced hypervolemia at 2800m altitude. Aviat Space Environ Med 72: 2001; 72: 522-8.
• Greenleaf JE, CGR Jackson, G Geelen, LC Keil, H Hinghofer-Szalkay, JH Whittam. Plasma volume expansion with oral fluids in hypohydrated men at rest and during exercise. Aviat Space Environ Med. 1998; 69: 837-44
• Greenleaf JE, PA Farrell, JL Loomis, M Federle, J West, A Roessler, H. Hinghofer-Szalkay. Sodium chloride - citrate beverages attenuate hypovolemia in men resting 12 hr at 2,800 m altitude. Aviat Space Environ Med. 1998; 69: 936-43
• Greenleaf JE, PA Farrell, H Hinghofer-Szalkay. Dehydration at airline cabine altitude. Research & Technology: Human Exploration and Development of Space Enterprise: Astronaut Health / Countermeasures. NASA TM 112195 (1996), pp. 141-4
• Greenleaf JE, Geelen G, Jackson CGR, Saumet JL, Juhos LT, Keil LC, Fegan-Meyer D, Dearborn A, Hinghofer-Szalkay H, Whittam JH. Vascular uptake of rehydration fluids in hypohydrated men at rest and exercise. NASA TM-103942: August 1992.
• Greenleaf JE, Hinghofer-Szalkay H. Plasma volume methodology: Evans blue, Hb-Hct and mass density transformations. NASA TM 86834, Washington D.C. 1985.

Other spaceflight-relevant publications

• Hinghofer-Szalkay H. Gravity, the hydrostatic indifference concept and the cardiovascular system. Eur J Appl Physiol 2011; 111: 163-74
  
• Hinghofer-Szalkay HG. The Brittle Bones of Deconditioning. Chapter 7 in: JE Greenleaf (ed).: Deconditioning and Reconditioning. CRC Press LLC (ISBN 0-415-30650-7), 2004, pp. 99-125
  
• Hinghofer-Szalkay H, Z Laszlo, D Jezova, A Rössler, B Haditsch, K Pilz, H Passath, H Scharfetter. Bed rest immobilization with various oral sodium supply: Plasma hormones and body fluids. Endocrine Regulations 2002; 36: 151-9
• Loeppky JA, Luther DK, Maes D, Riboni K, Hinghofer-Szalkay H, Charlton GA, Icenogle MV. Plasma volume by Evans blue: effects of eating and comparison with other methods at altitude. Aviat Space Environ Med 2002; 73: 902-6
• Noskov VB, Hinghofer-Szalkay H, Kvetnansky R. The volume regulation of humans during space flights aboard space station MIR. Symposium "Orbital station Mir: biomedical investigations" - XIIth Conference on Space Biology and Aerospace Medicine, Moscow, p. 543-4
• Hinghofer-Szalkay H, Loder I, Rössler A, Jezova D. Cardiovascular regulation during combined (LBNP/HDT vs. LBPP/HUT) stimulation. Abstracts: 8th European Symposium on Life Sciences Research in Space, and 23rd Ann. Int'l Gravitational Physiology Meeting, 2-7 June 2002, Stockholm. ESA SP-501, p. 143
• Hinghofer-Szalkay H, Rössler A, Scharfetter H, Pilz K, Laszlo Z. LBNP response after simulated weightlessness with varied oral sodium supply. Abstracts: 8th European Symposium on Life Sciences Research in Space, and 23rd Ann. Int'l Gravitational Physiology Meeting, 2-7 June 2002, Stockholm. ESA SP-501, p. 146Roessler A, Noskov V, Laszlo Z, Polyakov VV, Hinghofer-Szalkay H. Permanent depression of plasma cGMP during long-term space flight. Physiol Res 2001; 50: 83-90.
• Hinghofer-Szalkay HG, Laszlo Z, Roessler A, Haditsch B, Rothaler A, Unterlerchner M, Woellik U. LBNP-induced changes in plasma cGMP with and without head down tilt bed rest. J Gravit Physiol 1999; 6: P 105-6.
• Hinghofer-Szalkay HG, Noskov VB, Rössler A, Grigoriev AI, Kvetnansky R, Polyakov VV. Endocrine status and LBNP-induced hormone changes during a 438-day space flight. Aviat Space Environ Med. 1999; 70: 1-5.
• Grigoriev AI, VB Noskov, VV Polyakov, DV Vorobiev, IA Nichiporuk, HG Hinghofer-Szalkay, A Rössler, R Kvetnansky, L Macho. Dynamics of the hormonal regulation during LBNP sessions in (a) long-term space mission. Aviakosm Ecol Med. 1998; 32: 18-23.
• Loeppky JA, Icenogle M, Scotto P, Robergs R, Hinghofer-Szalkay H, Roach RC. Pulmonary ventilation during simulated altitude, normobaric hypoxia and normoxic hypobaria in humans. Resp Physiol. 1997; 107: 231-9.
• H. Hinghofer-Szalkay (ed): Special issue on Spaceflight medicine, Wiener Medizinische Wochenschrift 1994; 143/23-24
• Noskov VB, Sukhanov YV, Volkov AA, Hinghofer-Szalkay H, König E, Sauseng-Fellegger G, Viehböck F, Kvetnansky R, Jezova D, Macho L. Assessment of the reactivity of cosmonaut´s hormonal regulation system during LBNP test during Soviet-Austrian flight onboard orbital station "MIR". Aerosp Environ Med. 1994; 28: 33-7
• Hinghofer-Szalkay H, Noskov V, Schmied J, Roehrer R, Viehboeck F, Koenig EM, Sauseng-Fellegger G, Zambo-Polz C, Heimel H, Grigoriev AI. Changes of blood / plasma composition with LBNP on ground and in space in one subject. Aviat Space Environ Med.  1994; 65: 214-9
• Hinghofer-Szalkay HG, Noskov V, Jezova D, Sauseng-Fellegger G, Fueger GF, Sukhanov Y, Koenig EM, Zambo-Polz C, Barowitsch C, Viehboeck F, Macho L, Kvetnansky R, Grigoriev A I. Hormonal changes with lower body suction on 6^th day in weightlessness in one cosmonaut. Aviat Space Environ Med.  1993; 64: 1000-5
• Austrian Society for Aerospace Medicine (ed.): Health from Space Research 1992; ISBN 3-211-82413-8, Springer Verlag, Wien / New York
  

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