Medical University of Graz

 
 
  Group members
Dagmar Kratky
Elma Aflaki
Prakash Doddapattar
Anton Ibovnik
Silvia Povoden Branislav Radovic

Link to the Austrian Science Foundation FWF Link to the Austrian Science Foundation FWF

  Prakash Chandak, MSc.
PhD student



prakash.chandak@medunigraz.at
  Institute of Molecular Biology and Biochemistry
Center of Molecular Medicine
Medical University of Graz
Harrachgasse 21/III
8010 Graz, Austria

Phone: +43 (316) 380 4199
Fax: +43 (316) 380 9615

Curriculum Vitae

 

 
 

Research area

  • Investigating lipolysis in macrophages

  • Elucidating the role of adipose triglyceride lipase in macrophages

  • Investigating the consequences of adipose triglyceride lipase deficiency on atherosclerosis

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    Publications

  • Chandak PG, Radovic B, Aflaki E, Kolb D, Buchebner M, Frohlich E, Magnes C, Sinner F, Haemmerle G, Zechner R, Tabas I, Levak-Frank S and Kratky D. 2010. Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase. J Biol Chem, 285:20192-20201.  [pdf]

  • Buchebner M, Pfeifer T, Rathke N, Chandak PG, Lass A, Schreiber R, Kratzer A, Zimmermann R, Sattler W, Koefeler H, Froehlich E, Kostner GM, Birner-Gruenberger R, Chiang KP, Haemmerle G, Zechner R, Levak-Frank S, Cravatt BF and Kratky D. 2010. Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363. J Lipid Res, 51:2896-2908.  [pdf]

  • Kratzer A, Buchebner M, Pfeifer T, Becker TM, Uray G, Miyazaki M, Miyazaki-Anzai S, Ebner B, Chandak PG, Kadam RS, Calayir E, Rathke N, Ahammer H, Radovic B, Trauner M, Hoefler G, Kompella UB, Fauler G, Levi M, Levak-Frank S, Kostner GM, and Kratky D. 2009. Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia. J Lipid Res, 50:312-326.  [pdf]

  • Anandharajan, R; Sayyed, SG; Doshi, LS; Dixit, P; Chandak, PG; Dixit, AV; Brahma, MK; Deshmukh, NJ; Gupte, R; Damre, A; Suthar, J; Padigaru, M; Sharma, SD; Nemmani, KV 18F9 (4-(3,6-bis (ethoxycarbonyl)-4,5,6,7-tetrahydrothieno (2,3-c) pyridin-2-ylamino)-4-oxobutanoic acid) enhances insulin-mediated glucose uptake in vitro and exhibits antidiabetic activity in vivo in db/db mice. Metabolism. 2009; 58(10): 1503-1516

  • Chandak, PG; Gaikwad, AB; Tikoo, K Gallotannin ameliorates the development of streptozotocin-induced diabetic nephropathy by preventing the activation of PARP. Phytother Res. 2009; 23(1):72-77

  • Doshi, LS; Brahma, MK; Sayyed, SG; Dixit, AV; Chandak, PG; Pamidiboina, V; Motiwala, HF; Sharma, SD; Nemmani, KV Acute administration of GPR40 receptor agonist potentiates glucose-stimulated insulin secretion in vivo in the rat. Metabolism. 2009; 58(3): 333-343.

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    Oct 12, 2010                  dagmar.kratky@medunigraz.at                                             HOME                  MedUni Graz